Scientific Results

Oligonucletides direct syntheis on porous silicon chip

Year: 2008

Authors: De Stefano L., De Tommasi E., Rea I., Rotiroti L., Giangrande L., Oliviero G., Borbone N., Galeone A., Piccialli G.

Autors Affiliation: Istituto per la Microelettronica e Microsistemi – Unità di Napoli, Consiglio Nazionale delle Ricerche, via P. Castellino 111, I-80131 Napoli, Italy; Dipartimento di Chimica delle Sostanze Naturali, Università degli Studi di Napoli “Federico II”, Via D. Montesano 49, I-80131 Napoli, Italy

Abstract: A solid phase oligonucleotide (ON) synthesis on porous silicon (PSi) chip is presented. The prepared Si-OH surface were analyzed by FT-IR and the OH functions were quantified by reaction with 3’-phosphoramidite nucleotide building block. Short ONs were synthesized on the chip surface and the coupling yields evaluated.


Volume: 52      Pages from: 721  to: 722

KeyWords: Oligonucleotids; Porous Silicon;

This site uses cookies. If you decide to continue browsing we consider that you accept their use. For more information about cookies and how to delete them please read our Info Policy on cookies use.
Read more