Optical detection of very small nonfluorescent nanoparticles
Anno: 2006
Autori: Sandoghdar V., Klotzsch E., Jacobsen V., Renn A., Hekanson U., Agio M., Gerhardt I., Seelig J., Wrigge G.
Affiliazione autori: ETH, Phys Chem Lab, CH-8093 Zurich, Switzerland.
Abstract: We discuss an interferometric method for the optical detection of very small nonfluorescent nanoparticles. In particular, we show that single gold nanoparticles with a diameter as small as 5 nm can be detected. We discuss the potential of such tiny particles as optical labels for biological studies. Furthermore, we show that our interferometric method can be also used for the detection and tracking of unlabelled biological nano-entities such as viruses or microtubuli.
Giornale/Rivista: CHIMIA
Volume: 60 (11) Da Pagina: A761 A: A764
Parole chiavi: interferometric detection; label-free; nanoparticle; optical microscopy; particle trackingDOI: 10.2533/chimia.2006.761Citazioni: 7dati da “WEB OF SCIENCE” (of Thomson Reuters) aggiornati al: 2025-05-18Riferimenti tratti da Isi Web of Knowledge: (solo abbonati)