Optical detection of very small nonfluorescent nanoparticles

Anno: 2006

Autori: Sandoghdar V., Klotzsch E., Jacobsen V., Renn A., Hekanson U., Agio M., Gerhardt I., Seelig J., Wrigge G.

Affiliazione autori: ETH, Phys Chem Lab, CH-8093 Zurich, Switzerland.

Abstract: We discuss an interferometric method for the optical detection of very small nonfluorescent nanoparticles. In particular, we show that single gold nanoparticles with a diameter as small as 5 nm can be detected. We discuss the potential of such tiny particles as optical labels for biological studies. Furthermore, we show that our interferometric method can be also used for the detection and tracking of unlabelled biological nano-entities such as viruses or microtubuli.

Giornale/Rivista: CHIMIA

Volume: 60 (11)      Da Pagina: A761  A: A764

Parole chiavi: interferometric detection; label-free; nanoparticle; optical microscopy; particle tracking
DOI: 10.2533/chimia.2006.761

Citazioni: 7
dati da “WEB OF SCIENCE” (of Thomson Reuters) aggiornati al: 2025-05-18
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