A perturbation approach to characterize absorptive inclusions in diffusing media by time-resolved contrast measurements

Anno: 2004

Autori: Esposito R., De Nicola S., Lepore M., Delfino I., Indovina P.L.

Affiliazione autori: Dipartimento di Fisica, Università ‘Federico II’, Compl. Univ. Montesantangelo,
Via Cintia, 80126 Napoli, Italy;
Istituto Nazionale di Fisica della Materia, Unità di Napoli, Napoli, Italy;
Istituto di Cibernetica del CNR ‘E Caianiello’, Comprensorio A Olivetti, Via Campi Flegrei 34, 80078 Pozzuoli, Italy;
Dipartimento di Medicina Sperimentale, Seconda Università di Napoli, Italy
Biophysics and Nanoscience Centre, INFM, Environmental Science Department,
Università di Tuscia, Italy

Abstract: Time-resolved measurements of ultrashort light pulses transmitted through turbid scattering media have been performed to determine the possibilities and the limitations of a first-order perturbation approach to recover the absorption coefficient of different tissue-like cylindrical absorptive phantoms. The model accounts for the effect of a spatially varying absorption coefficient of an inclusion on the time-resolved transmittance. We have determined the absorption coefficient of the inhomogeneities located at the midplane of a scattering cell by fitting the diffusion approximation-based perturbation model to the experimental time-resolved contrast measurements. The accuracy of the model predictions is discussed. An error analysis of the fitting procedure is also presented.

Giornale/Rivista: JOURNAL OF OPTICS A-PURE AND APPLIED OPTICS

Volume: 6 (7)      Da Pagina: 736  A: 741

Parole chiavi: biological media; diffusion; scattering; time resolved; ultrashort pulses
DOI: 10.1088/1464-4258/6/7/013

Citazioni: 7
dati da “WEB OF SCIENCE” (of Thomson Reuters) aggiornati al: 2024-05-12
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